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Injection: Injection: For I.V. injection, each single dose vial containing lyophilized powder of omeprazole 40 mg should be reconstituted with 10 mL of water for injection. The resulting concentration is 4 mg/mL of omeprazole. Omeprazole 40 mg should be given slowly (over a period of 5 minutes) as an intravenous injection.
Infusion: For I.V. infusion, the single dose vial should be dissolved in either 100 mL Sodium chloride injection (0.9% w/v) or 100 mL of glucose intravenous infusion (5% w/v). No other solution should be used for the infusion. The infusion should be given over a period of 20-30 minutes.
The reconstituted solution should be used within 3 hours of preparation and any unused portion should be discarded. The reconstituted solution should not be refrigerated.
Incompatibilities: Infusions with low pH should not be used for diluting omeprazole injection as fading & discoloration of solution can occur.
